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Study #: 2418 Published: 11/2008 Pages: 238 Full Study Price: US$ 4,600 Per Page Price: US$ 30.00 Biochips to 2012 - Market Research, Market Share, Market Size, Sales, Demand Forecast, Market Leaders, Company Profiles, Industry Trends US demand for biochip products and services will grow nearly ten percent annually through 2012. Growth will be led by uses in drug discovery and epidemiological research, with protein characterization and analysis providing the fastest expanding technologies. Contract research and outsourcing will post the strongest gains among biochip services. This study analyzes the $1.6 billion US biochips industry. It presents historical demand data for the years 1997, 2002 and 2007, and forecasts for 2012 and 2017 by technology (gene expression, SNP identification and genotyping, proteomic), product (e.g., microarrays, biochip reagents and consumables, biochip instruments, biochip software), service, application (e.g., drug discovery, life science research, in vitro diagnostic testing, disease management, forensic medicine, drugs-of-abuse testing) and market (e.g., pharmaceutical companies, biotechnology companies, colleges and universities, medical providers). The study also considers market environment factors, details industry structure, evaluates company market share and profiles 26 industry players, including Illumina, Affymetrix and Applied Biosystems.
TABLE OF CONTENTS
SECTION PAGE
INTRODUCTION ix
GLOSSARY OF TERMS xi
I. EXECUTIVE SUMMARY 1
II. MARKET ENVIRONMENT 4
General 4
Macroeconomic Trends 4
Demographic Patterns 9
Trends in Health Care 11
Health Insurance Coverage 12
Diseases & Disorders 15
Acute Conditions 16
Chronic Conditions 17
National Health Expenditures 20
Types 21
Sources 23
Medical Providers 23
Acute Care Hospitals 24
Outpatient Clinics 25
Skilled Nursing Homes 26
Physicians 26
Patient Activity 26
Acute Care Hospital Admissions 29
Surgical Procedures 29
Outpatient Episodes 29
Diagnostic Tests 30
Pharmaceutical Industry Trends 31
Regulation 32
Research & Development 33
Product Shipments 35
Therapeutic Classes 36
Trends in Shipments 37
Trends in In Vitro Diagnostics 38
Regulation 39
Research & Development 40
Product Shipments 41
Life Science Research Trends 43
Funding 44
Activities 45
Biochip Market Overview 46
Markets Served 48
Demand Patterns 48
US Trade 49
International Markets 50
III. BIOCHIP TECHNOLOGIES 53
General 53
Genomic Technology 55
DNA Structure 55
Genetic Variants 57
Gene Expression 57
SNP Identification & Genotyping 59
Proteomics 61
Protein Structure 62
Commercial Applications 63
Biochip Production Methods 64
Photolithography 64
Microfluidic Technology 65
Sample Preparation & Hybridization Processes 66
Biochip Detection Methods 68
Biochip Data Analysis 69
Competitive Technologies 70
Research Technologies 71
In Vitro Diagnostic (IVD) Technologies 72
Drug Discovery Technologies 73
IV. BIOCHIP PRODUCTS & SERVICES 74
General 74
Biochip Products 75
Biochips (Microarrays) 77
DNA Chips 79
Applications 82
Producers 83
Protein Chips 86
Applications 87
Producers 88
Laboratory Chips 90
Applications 92
Producers 93
Biochip Reagents & Consumables 95
Extraction Reagents 96
Labeling Kits 97
Other Reagents & Consumables 98
Biochip Instruments 99
Detection Instruments 101
Technologies 101
Products & Producers 102
Production Instruments 106
Production Methods 107
Products & Producers 108
Sample Preparation & Hybridization Instruments 109
Sample Preparation Instruments 110
Hybridization Instruments 112
Biochip Software 113
Open Programs 115
Closed Programs 117
Biochip Services 119
Contract & Related Services 120
Maintenance, Repair & Technical Support Services 123
V. BIOCHIP APPLICATIONS 124
General 124
Drug Discovery 126
Gene Expression 129
SNP Identification & Genotyping 129
Proteomics 130
Life Science Research 131
In Vitro Diagnostic Testing 134
Disease Management 137
Forensic Medicine 139
Drugs-of-Abuse Testing 141
Other Applications 143
Agriculture 144
Defense & Military 145
Industrial & Environmental Applications 146
VI. BIOCHIP MARKETS 147
General 147
Pharmaceutical Companies 149
Market Trends 150
Biochip Trends 151
Biotechnology Companies 153
Colleges & Universities 155
Medical Providers 157
Hospitals 158
Clinical Laboratories 159
Other Medical Providers 160
Government Agencies 160
Other Markets 162
VII. INDUSTRY STRUCTURE 165
General 165
Market Share 165
Competitive Strategies 172
Mergers & Acquisitions 174
Licensing & Related Agreements 175
Research & Development 178
Marketing & Distribution 179
Manufacturing Activities 180
Company Profiles 181
Affymetrix Incorporated 182
Agilent Technologies Incorporated 187
Applera Corporation, see Applied Biosystems
Applied Biosystems Incorporated 189
Beckman Coulter Incorporated 191
Becton, Dickinson and Company 194
Bio-Rad Laboratories Incorporated 195
bioMerieux SA 198
BioTrove Incorporated 199
Caliper Life Sciences Incorporated 201
Cepheid 203
Clontech Laboratories Incorporated, see Takara Holdings
CombiMatrix Corporation 205
Fluidigm Corporation 207
General Electric Company 209
Helicos BioSciences Corporation 211
Illumina Incorporated 212
Invitrogen Corporation 215
Johnson & Johnson 217
MDS Incorporated 219
Micronics Incorporated 221
Molecular Devices Corporation, see MDS
Pacific Biosciences of California Incorporated 222
PerkinElmer Incorporated 223
QIAGEN NV 226
Roche Holding Limited 228
SEQUENOM Incorporated 230
Siemens AG 232
Solexa Incorporated, see Illumina
Takara Holdings Incorporated 234
Veridex LLC, see Johnson & Johnson
Other Companies Mentioned in the Study 236
LIST OF TABLES
TABLE NUMBER PAGE
SECTION I -- EXECUTIVE SUMMARY
Summary Table 3
SECTION II -- MARKET ENVIRONMENT
1 Macroeconomic Indicators 9
2 Population by Age Group 11
3 Health Insurance Coverage of the US Population 15
4 Acute Conditions by Type 17
5 Chronic Conditions by Type 18
6 National Health Expenditures by Type & Source 21
7 Medical Providers by Type 24
8 Patient Activity by Type 28
9 Pharmaceutical Research & Development Expenditures
by Type & Object 35
10 Pharmaceutical Shipments by Therapeutic Class 36
11 In Vitro Diagnostic (IVD) Product Demand
by Methodology & Type 43
12 Life Science Research & Development Expenditures
by Objective & Performing Sector 45
13 Biochip Product & Service Demand, 1998-2007 47
14 US Trade in Biochip Products 50
15 World Biochip Product & Service Demand 52
SECTION III -- BIOCHIP TECHNOLOGIES
1 Biochip Product & Service Demand by Technology 54
2 Gene Expression - Biochip Product & Service Demand 59
3 SNP Identification & Genotyping - Biochip Product &
Service Demand 61
4 Proteomic & Related Technologies - Biochip Product &
Service Demand 62
SECTION IV -- BIOCHIP PRODUCTS & SERVICES
1 Biochip Product & Service Demand by Category 75
2 Biochip Product Demand by Type 76
3 Biochip (Microarray) Demand by Type 78
4 DNA Chip (Microarray) Demand by Application 81
5 Protein Chip (Microarray) Demand by Application 87
6 Laboratory Chip (Microarray) Demand by Application 92
7 Biochip Reagent & Consumable Demand by Application 96
8 Biochip Instrument Demand by Type 100
9 Biochip Detection Instrument Demand by Application 101
10 Biochip Production Instrument Demand by Application 107
11 Biochip Sample Preparation & Hybridization Instrument
Demand by Application 110
12 Biochip Software Demand by Application 115
13 Biochip Service Demand by Type 120
SECTION V -- BIOCHIP APPLICATIONS
1 Biochip Product & Service Demand by Application 125
2 Drug Discovery Demand - Biochip Products & Services 128
3 Life Science Research Demand - Biochip Products
& Services 134
4 In Vitro Diagnostic Testing Demand - Biochip Products
& Services 137
5 Disease Management Demand - Biochip Products
& Services 139
6 Forensic Medicine Demand - Biochip Products & Services 141
7 Drugs-of-Abuse Testing Demand - Biochip Products
& Services 143
8 Biochip Product & Service Demand in Other Applications 144
SECTION VI -- BIOCHIP MARKETS
1 Biochip Product & Service Demand by Market 148
2 Pharmaceutical Industry Demand - Biochip Products
& Services 150
3 Biotechnology Industry Demand - Biochip Products
& Services 154
4 College & University Demand - Biochip Products & Services 157
5 Medical Provider Demand - Biochip Products & Services 158
6 Government Agency Demand - Biochip Products & Services 162
7 Biochip Product & Service Demand in Other Markets 164
SECTION VII -- INDUSTRY STRUCTURE
1 Biochip Revenues by Company, 2007 167
2 Selected Acquisitions & Divestitures 175
3 Selected Cooperative Agreements 177
LIST OF CHARTS
CHART NUMBER PAGE
SECTION III -- BIOCHIP TECHNOLOGIES
1 Biochip Product & Service Demand by Technology, 2007 55
SECTION IV -- BIOCHIP PRODUCTS & SERVICES
1 Biochip Product Demand by Type, 2007 77
2 Biochip (Microarray) Demand by Type, 2007 79
3 Biochip Instrument Demand by Type, 2007 100
SECTION V -- BIOCHIP APPLICATIONS
1 Biochip Product & Service Demand by Application, 2007 126
2 Drug Discovery Demand for Biochip Products & Services
by Type, 2007 128
SECTION VI -- BIOCHIP MARKETS
1 Biochip Product & Service Demand by Market, 2007 149
SECTION VII -- INDUSTRY STRUCTURE
1 Biochip Products & Services Market Share by
Company, 2007 168
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