| Inform your business decisions - authoritative market research - reliable forecasts Learn more about our industry study - purchase by the page or the full report: Study #: 2294 Published: 03/2008 Pages: 338 Full Study Price: US$ 4,500 Per Page Price: US$ 35.00 (text) | 60.00 (table) Drug Delivery Systems to 2012 - Market Research, Market Share, Market Size, Sales, Demand Forecast, Market Leaders, Company Profiles, Industry Trends US demand for drug delivery systems will grow 10 percent annually through 2012. Oral types will remain the largest drug delivery category while parenteral, inhalation and implantable systems grow the fastest. Parenteral formulations will eventually surpass oral dosages as the largest product group. This study analyzes the $80.2 billion US drug delivery system industry. It presents historical demand data for the years 1997, 2002 and 2007, and forecasts for 2012 and 2017 by material (e.g., sterile and purified water, synthetic polymers, cellulose derivatives, minerals); type (e.g., oral, parenteral, inhalation, transdermal, implantable); and application. The study also considers market environment factors, details industry structure, evaluates company market share and profiles 30 leading industry players, including GlaxoSmithKline, Genentech, AstraZeneca, Abbott Laboratories, Wyeth, Eli Lilly, Johnson & Johnson, Sanofi-Aventis, Amgen, and Pfizer.
TABLE OF CONTENTS
SECTION PAGE
INTRODUCTION xi
I.EXECUTIVE SUMMARY 1
II.MARKET ENVIRONMENT 4
General 4
Macroeconomic Trends 5
Demographic Patterns 7
Health Care Trends 9
Health Insurance 10
Medical Conditions 12
Acute Conditions 12
Chronic Conditions 14
National Health Expenditures 18
Medical Providers 22
Outpatient Clinics 23
Skilled Nursing Homes 24
Acute Care Hospitals 24
Physicians 25
Patient Activity 26
Acute Care Hospital Admissions 27
Surgical Procedures 28
Outpatient Visits 28
Pharmaceutical Market Overview 29
Regulation 31
Research & Development 31
Demand Patterns & Forecasts 32
Therapeutic Classes 33
Generic Competition 35
Dosage Formulations 37
Regulatory Classifications 39
III.DRUG DELIVERY MATERIALS 41
General 41
Sterile & Purified Water 43
Synthetic Polymers 45
Polyethylene Glycol (PEG) 46
Acrylic Polymers 48
Carbomers 48
Methacrylate Copolymers 48
Polyethylene Oxide 50
Polyvinyl Alcohol 51
Other Synthetic Polymers 52
Cellulose Derivatives 53
Ethyl Cellulose 54
Hydroxypropyl Methylcellulose (HPMC) 55
Other Cellulose Derivatives 56
Minerals 56
Mineral Hydrocarbons 57
Petrolatum 57
Mineral Oil 58
Mineral Hydrocarbon Waxes 58
Other Minerals 59
Attapulgite 59
Calcium Carbonate 59
Calcium Silicate 60
Electrolytes 60
Other Drug Delivery Materials 61
Starch Compounds 62
Cyclodextrins 62
Dextrates 63
Dextrin 63
Maltodextrin 63
Sugars & Polyols 64
Sucrose 64
Sorbitol 65
Lactose 65
Mannitol 66
Natural Gums 67
All Other Drug Delivery Materials 67
IV.DRUG DELIVERY SYSTEMS OVERVIEW 69
General 69
Types of Drug Delivery Systems 71
Historical Demand Patterns 72
Regulation 75
Research & Development 76
US Trade 77
International Markets 78
V.ORAL DRUG DELIVERY SYSTEMS 80
General 80
Controlled-Release Formulations 83
Technologies 85
Coated Systems 85
Diffusion Systems 88
Reservoir Systems 90
Chewable Tablets 92
Orally Disintegrating Tablets 95
Nanoparticulate Formulations 97
Ethical Pharmaceuticals 98
Over-the-Counter Drugs 101
Transmucosal Formulations 102
VI.PARENTERAL DRUG DELIVERY SYSTEMS 106
General 106
Therapeutic Monoclonal Antibodies 108
Technology 110
Anti-Cancer Agents 114
Other Therapeutic Monoclonal Antibodies 119
Products in Development 125
Prefilled Syringes 126
Applications 128
Injectors 129
Cartridges & Insulin Pens 131
Encapsulated Systems 133
Polymer-Protected Systems 135
PEGylated Formulations 135
Other Polymer-Protected Pharmaceuticals 139
Liposomes 141
Developmental Activities 143
Premixed IV Solutions 151
Mini-Bags 152
Bag/Vial Infusion Systems 153
Applications 154
VII. INHALATION, TRANSDERMAL & IMPLANTABLE
DRUG DELIVERY SYSTEMS 155
General 155
Inhalation Drug Delivery Systems 157
Dry Powder Formulations 158
Devices & Technologies 159
Applications 162
Metered Dose Formulations 163
Devices & Technologies 163
Applications 167
Transdermal Drug Delivery Systems 168
Products & Technologies 169
Developers & Suppliers 171
Applications 173
Implantable Drug Delivery Systems 180
Drug-Eluting Stents 181
Drug Inserts 183
Brachytherapy 185
VIII.APPLICATIONS 188
General 188
Central Nervous System Agents 190
Respiratory Agents 194
Hormones & Related Agents 196
Gastrointestinal Agents 201
Cardiovascular Agents 203
Anti-Infective Agents 207
Nutritional Agents 210
Biologicals 212
Genito-Urinary Agents 214
Other Therapies 216
IX.INDUSTRY STRUCTURE 220
General 220
Developmental Revenues 221
Market Share 225
Competitive Strategies 226
Mergers & Acquisitions 228
Licensing & Related Agreements 231
Marketing & Distribution 238
Manufacturing
239
Company Profiles 240
Alkermes Incorporated 241
AptarGroup Incorporated 244
Aradigm Corporation 246
Associated British Foods plc 249
Baxter International Incorporated 251
Becton, Dickinson and Company 256
Catalent Pharma Solutions Incorporated 260
Cephalon Incorporated 263
Consort Medical plc 267
Corium International Incorporated 269
CyDex Pharmaceuticals Incorporated 271
Depomed Incorporated 272
Dow Corning Corporation 274
DURECT Corporation 275
Elan Corporation plc 278
Emisphere Technologies Incorporated 283
Eurand NV 285
Flamel Technologies SA 289
Genzyme Corporation 292
Hospira Incorporated 294
Johnson & Johnson 298
Nastech Pharmaceutical Company Incorporated 304
Nektar Therapeutics 307
Nitto Denko Corporation 312
NOF Corporation 314
Penwest Pharmaceuticals Company 316
ReAble Therapeutics Incorporated 318
Safety Syringes Incorporated 320
SPI Pharma, see Associated British Foods
StrataGent Life Sciences, see Corium International
3M Company 321
Valeritas LLC 325
Valois SAS, see AptarGroup
Other Companies Mentioned in Study 327
LIST OF TABLES
TABLE NUMBER PAGE
SECTION I -- EXECUTIVE SUMMARY
Summary Table 3
SECTION II -- MARKET ENVIRONMENT
1 Macroeconomic Indicators 7
2 Population by Age Group 9
3 Acute Conditions by Type 14
4 Chronic Conditions by Type 17
5 National Health Expenditures by Type 21
6 Medical Providers by Type 23
7 Patient Activity by Type 27
8 Pharmaceutical Demand by Therapeutic Class 35
9 Pharmaceutical Demand by Commercial Status 37
10 Pharmaceutical Demand by Dosage Formulation 38
11 Pharmaceutical Demand by Regulatory Classification 40
SECTION III -- DRUG DELIVERY MATERIALS
1 Drug Delivery Material Demand by Type 42
2 Sterile & Purified Water Demand in Drug Delivery 45
3 Synthetic Polymer Demand in Drug Delivery 46
4 Cellulose Derivative Demand in Drug Delivery 53
5 Mineral Demand in Drug Delivery 57
6 Other Material Demand in Drug Delivery 62
SECTION IV -- DRUG DELIVERY SYSTEMS OVERVIEW
1 Drug Delivery System Demand by Dosage Formulation 70
2 Drug Delivery System Demand, 1997-2007 75
3 US Trade in Drug Delivery Systems 78
4 World Drug Delivery System Demand by Region 79
SECTION V -- ORAL DRUG DELIVERY SYSTEMS
1 Oral Drug Delivery System Demand by Type 82
2 Oral Controlled-Release Drug Delivery System Demand 84
3 Coated Controlled-Release Drug Delivery System Demand 88
4 Diffusion Controlled-Release Drug Delivery System Demand 90
5 Reservoir Controlled-Release Drug Delivery System Demand 92
6 Chewable Tablet Demand by Therapeutic Class 94
7 Orally Disintegrating Tablet Demand by Therapeutic Class 97
8 Nanoparticulate Oral Drug Delivery System Demand by
Therapeutic Class 98
9 Oral Transmucosal Drug Delivery System Demand by
Therapeutic Class 105
SECTION VI -- PARENTERAL DRUG DELIVERY SYSTEMS
1 Parenteral Drug Delivery System Demand by Type 107
2 Therapeutic Monoclonal Antibody Demand by Therapeutic
Class 110
3 Therapeutic Monoclonal Antibodies Approved for US Sale 112
4 Prefilled Syringe Demand by Therapeutic Class 127
5 Encapsulated Parenteral Drug Delivery System Demand
by Type & Therapeutic Class 134
6 Premixed IV Solution Demand by Therapeutic Class 152
SECTION VII -- INHALATION, TRANSDERMAL & IMPLANTABLE DRUG DELIVERY SYSTEMS
1 Other Drug Delivery System Demand by Type 156
2 Inhalation Drug Delivery System Demand by Type &
Therapeutic Class 158
3 Transdermal Drug Delivery System Demand by Therapeutic
Class 169
4 Implantable Drug Delivery System Demand by Type &
Therapeutic Class 181
SECTION VIII -- APPLICATIONS
1 Drug Delivery System Demand by Therapeutic Class 189
2 Central Nervous System Drug Delivery Demand by Type 193
3 Respiratory Drug Delivery Demand by Type 196
4 Hormone & Related Drug Delivery Demand by Type 201
5 Gastrointestinal Drug Delivery System Demand by Type 203
6 Cardiovascular Drug Delivery System Demand by Type 207
7 Anti-Infective Drug Delivery System Demand by Type 209
8 Nutritional Delivery System Demand by Type 212
9 Biological Delivery System Demand by Type 214
10 Genito-Urinary Drug Delivery System Demand 216
11 Drug Delivery System Demand in Other Therapies 219
SECTION IX -- INDUSTRY STRUCTURE
1 Drug Delivery Revenues by Company, 2007 223
2 Selected Acquisitions & Divestitures 230
3 Selected Cooperative Agreements 232
LIST OF CHARTS
CHART NUMBER PAGE
SECTION III -- DRUG DELIVERY MATERIALS
1 Drug Delivery Material Demand by Type, 2007 43
SECTION IV -- DRUG DELIVERY SYSTEMS OVERVIEW
1 Drug Delivery System Demand by Dosage Formulation, 2007 70
SECTION V -- ORAL DRUG DELIVERY SYSTEMS
1 Oral Drug Delivery System Demand by Type, 2007 82
SECTION VI -- PARENTERAL DRUG DELIVERY SYSTEMS
1 Parenteral Drug Delivery System Demand by Type, 2007 108
SECTION VII -- INHALATION, TRANSDERMAL & IMPLANTABLE DRUG DELIVERY SYSTEMS
1 Inhalation, Transdermal & Implantable Drug Delivery
System Demand by Type, 2007 157
SECTION VIII -- APPLICATIONS
1 Drug Delivery System Demand by Therapeutic Class, 2007 190
SECTION IX -- INDUSTRY STRUCTURE
1 US Drug Delivery Product Sales by Company, 2007 225
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