Excipients

As Quoted In Business Standard

Gains will accelerate as excipients continue to add value to pharmaceuticals by improving properties such as the controlled release or improved absorption of active ingredients.

US demand to rise 4.3% annually through 2018

Demand for pharmaceutical excipients in the US is projected to rise 4.3 percent per year to $2.0 billion in 2018. While continued growth in pharmaceutical output will be the primary driver of increases in excipient demand, gains will accelerate as excipients play a larger role in bringing additional value to pharmaceutical products by improving properties such as the controlled release or improved absorption of active ingredients. However, the growing share of generics in the pharmaceutical industry will continue to make the cost of excipients an important factor for pharmaceutical manufacturers seeking to reduce production expenses. As a result, the best growth prospects are expected for products that offer a good balance among performance, compatibility with other excipients, and overall cost. Excipients for use in parenteral preparations will offer good opportunities as output of these formulations is expected to rise at a healthy pace going forward. Excipients in oral formulations such as tablets and capsules will also see strong growth as shipments of oral preparations are expected to accelerate.

Specialty blends to benefit from industry trends

A major development in the excipient and pharmaceutical industries is the increased dependence on specialty excipient blends, which can add value to a pharmaceutical product by differentiating it from competitive products and by optimizing the production process. These value-added excipient blends are often formulated for use in specific manufacturing processes such as direct compression or wet granulation, and are optimized for certain performance characteristics such as delayed- or extended-release oral tablets. Product differentiation will play an increasingly important role going forward as generic pharmaceutical products increase their market share and as consumers take a more active role in choosing their drugs from among a wide range of products with the same active pharmaceutical ingredients.

Product versatility to be key factor, favor polymers

Product versatility will be a key factor impacting product mix in excipient demand going forward, especially as specialty excipient blends play an increasingly important role in pharmaceutical formulation. Polymers -- including cellulose derivatives, povidone, starch, polyethylene glycol, acrylic polymers, and natural gums -- are expected to benefit especially from this trend as many of these products can function in multiple applications and are easily formulated with other excipients. These favorable characteristics will serve to offset the higher prices associated with some polymers.

Study coverage

This study analyzes the $1.6 billion US excipients industry. It presents historical demand data for 2003, 2008 and 2013, and forecasts for 2018 and 2023 by product (e.g., polymers, alcohols, minerals, gelatin, sugars) and application (e.g., fillers and diluents, binders, suspension and viscosity agents, coatings, solvents, flavoring agents, capsules, disintegrants, colorants, lubricants and glidants, preservatives).

The study also considers market environment factors, details industry structure, evaluates company market share and profiles 47 industry players, including Dow Chemical, Ashland and FMC.

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Purchase Excipients by the Section

  1. Excipients

    $5,100.00

    1. 1 INTRODUCTION

      $120.00

    2. 2 EXECUTIVE SUMMARY

      $158.00

      1. Table | EXCIPIENT DEMAND BY TYPE

    3. 3 MARKET ENVIRONMENT

      $1,665.00

      1. 3.1 General

        $82.00

      2. 3.2 Economic Factors

        $241.00

        1. Table | MACROECONOMIC INDICATORS

      3. 3.3 Demographic Patterns

        $212.00

        1. Table | POPULATION & HOUSEHOLDS

      4. 3.4 Health Care Trends

        $442.00

        1. 3.4.1 National Health Expenditures

          $213.00

          1. Table | NATIONAL HEALTH EXPENDITURES

        2. 3.4.2 Medical Conditions

          $206.00

          1. Table | CHRONIC CONDITIONS BY TYPE

          2. Table | ACUTE CONDITIONS BY TYPE

      5. 3.5 Pharmaceuticals

        $339.00

        1. Table | PHARMACEUTICAL SUPPLY & DEMAND

        2. 3.5.1 Therapeutic Class

          $82.00

          1. Table | PHARMACEUTICAL SHIPMENTS BY THERAPEUTIC CLASS

        3. 3.5.2 Dosage Formulations

          $91.00

          1. Table | PHARMACEUTICAL SHIPMENTS BY DOSAGE FORMULATION

        4. 3.5.3 Distribution Classifications

          $88.00

          1. Table | PHARMACEUTICAL SHIPMENTS BY DISTRIBUTION CLASSIFICATION

        5. 3.5.4 Commercial Status

          $82.00

          1. Table | PHARMACEUTICAL SHIPMENTS BY COMMERCIAL STATUS

      6. 3.6 Regulatory Overview

        $95.00

      7. 3.7 Historical Market Trends

        $82.00

        1. Table | EXCIPIENT MARKET, 2003-2013

      8. 3.8 Pricing Trends

        $105.00

        1. Table | PHARMACEUTICAL EXCIPIENT PRICING

      9. 3.9 Foreign Trade

        $82.00

      10. 3.10 International Markets

        $82.00

    4. 4 PRODUCTS

      $5,132.00

      1. 4.1 General

        $235.00

        1. Table | PHARMACEUTICAL EXCIPIENT DEMAND BY PRODUCT GROUP

        2. CHART III-1 EXCIPIENT DEMAND BY PRODUCT: VALUE & VOLUME, 2013

      2. 4.2 Polymers

        $2,302.00

        1. Table | POLYMER EXCIPIENT DEMAND BY TYPE & APPLICATION

        2. CHART III-2 POLYMER EXCIPIENT DEMAND: VALUE & VOLUME, 2013

        3. 4.2.1 Cellulose Derivatives

          $893.00

          1. Table | CELLULOSE EXCIPIENT DEMAND BY TYPE & APPLICATION

          2. Table | MICROCRYSTALLINE CELLULOSE EXCIPIENT DEMAND BY APPLICATION

          3. Table | HYDROXYPROPYL METHYLCELLULOSE EXCIPIENT DEMAND BY APPLICATION

          4. Table | ETHYL CELLULOSE EXCIPIENT DEMAND BY APPLICATION

          5. Table | METHYL CELLULOSE EXCIPIENT DEMAND BY APPLICATION

          6. Table | CARBOXYMETHYLCELLULOSE EXCIPIENT DEMAND BY APPLICATION

          7. Table | CROSCARMELLOSE SODIUM EXCIPIENT DEMAND

          8. Table | OTHER CELLULOSE EXCIPIENT DEMAND BY APPLICATION

        4. 4.2.2 Povidone

          $128.00

          1. Table | POVIDONE EXCIPIENT DEMAND BY APPLICATION

        5. 4.2.3 Starch Compounds

          $488.00

          1. Table | STARCH EXCIPIENT DEMAND BY TYPE & APPLICATION

          2. Table | PREGELATINIZED STARCH EXCIPIENT DEMAND BY APPLICATION

          3. Table | SODIUM STARCH GLYCOLATE EXCIPIENT DEMAND

          4. Table | OTHER STARCH EXCIPIENT DEMAND BY APPLICATION

        6. 4.2.4 Polyethylene Glycol

          $152.00

          1. Table | POLYETHYLENE GLYCOL EXCIPIENT DEMAND BY APPLICATION

        7. 4.2.5 Acrylic Polymers

          $187.00

          1. Table | ACRYLIC POLYMER EXCIPIENT DEMAND BY APPLICATION

        8. 4.2.6 Other Polymers

          $371.00

          1. Table | OTHER POLYMER EXCIPIENT DEMAND BY TYPE & APPLICATION

      3. 4.3 Alcohols

        $693.00

        1. Table | ALCOHOL EXCIPIENT DEMAND BY TYPE & APPLICATION

        2. 4.3.1 Propylene Glycol

          $91.00

          1. Table | PROPYLENE GLYCOL EXCIPIENT DEMAND BY APPLICATION

        3. 4.3.2 Glycerin

          $96.00

          1. Table | GLYCERIN EXCIPIENT DEMAND BY APPLICATION

        4. 4.3.3 Sorbitol

          $82.00

          1. Table | SORBITOL EXCIPIENT DEMAND BY APPLICATION

        5. 4.3.4 Other Alcohols

          $351.00

          1. Table | OTHER ALCOHOL EXCIPIENT DEMAND BY TYPE & APPLICATION

      4. 4.4 Minerals

        $860.00

        1. Table | MINERAL EXCIPIENT DEMAND BY TYPE & APPLICATION

        2. 4.4.1 Calcium Phosphate

          $102.00

          1. Table | CALCIUM PHOSPHATE EXCIPIENT DEMAND

        3. 4.4.2 Calcium Carbonate

          $86.00

          1. Table | CALCIUM CARBONATE EXCIPIENT DEMAND

        4. 4.4.3 Clay

          $109.00

          1. Table | CLAY EXCIPIENT DEMAND BY APPLICATION

        5. 4.4.4 Mineral Hydrocarbons

          $155.00

          1. Table | MINERAL HYDROCARBON EXCIPIENT DEMAND BY APPLICATION

        6. 4.4.5 Silicon Dioxide

          $82.00

          1. Table | SILICON DIOXIDE EXCIPIENT DEMAND BY APPLICATION

        7. 4.4.6 Titanium Dioxide

          $82.00

          1. Table | TITANIUM DIOXIDE EXCIPIENT DEMAND

        8. 4.4.7 Other Minerals

          $173.00

          1. Table | OTHER MINERAL EXCIPIENT DEMAND BY APPLICATION

      5. 4.5 Gelatin

        $215.00

        1. Table | GELATIN EXCIPIENT DEMAND BY APPLICATION

      6. 4.6 Sugars

        $414.00

        1. Table | SUGAR EXCIPIENT DEMAND BY TYPE & APPLICATION

        2. 4.6.1 Lactose

          $119.00

          1. Table | LACTOSE EXCIPIENT DEMAND BY APPLICATION

        3. 4.6.2 Sucrose

          $99.00

          1. Table | SUCROSE EXCIPIENT DEMAND BY APPLICATION

        4. 4.6.3 Other Sugar Excipients

          $146.00

          1. Table | OTHER SUGAR EXCIPIENT DEMAND BY APPLICATION

      7. 4.7 Other Pharmaceutical Excipients

        $966.00

        1. Table | OTHER PHARMACEUTICAL EXCIPIENT DEMAND BY TYPE & APPLICATION

        2. 4.7.1 Dyes & Pigments

          $82.00

        3. 4.7.2 Flavors

          $82.00

        4. 4.7.3 Surfactants

          $155.00

        5. 4.7.4 Acidulants

          $97.00

        6. 4.7.5 Antioxidants & Antimicrobials

          $90.00

        7. 4.7.6 All Other Compounds

          $375.00

    5. 5 APPLICATIONS

      $1,177.00

      1. 5.1 General

        $142.00

        1. Table | PHARMACEUTICAL EXCIPIENT DEMAND BY APPLICATION

        2. CHART IV-1 PHARMACEUTICAL EXCIPIENT DEMAND BY APPLICATION, 2013

      2. 5.2 Fillers & Diluents

        $105.00

        1. Table | FILLER & DILUENT EXCIPIENT DEMAND BY TYPE

      3. 5.3 Binders

        $130.00

        1. Table | BINDER EXCIPIENT DEMAND BY TYPE

      4. 5.4 Suspension & Viscosity Agents

        $82.00

        1. Table | SUSPENSION & VISCOSITY EXCIPIENT DEMAND BY TYPE

      5. 5.5 Coatings

        $87.00

        1. Table | COATING EXCIPIENT DEMAND BY TYPE

      6. 5.6 Solvents

        $89.00

        1. Table | SOLVENT EXCIPIENT DEMAND BY TYPE

      7. 5.7 Flavoring Agents

        $89.00

        1. Table | FLAVORING AGENT EXCIPIENT DEMAND BY TYPE

      8. 5.8 Capsules

        $150.00

        1. Table | CAPSULE EXCIPIENT DEMAND BY TYPE

      9. 5.9 Disintegrants

        $82.00

        1. Table | DISINTEGRANT EXCIPIENT DEMAND BY TYPE

      10. 5.10 Colorants

        $82.00

        1. Table | COLORANT EXCIPIENT DEMAND BY TYPE

      11. 5.11 Lubricants & Glidants

        $82.00

        1. Table | LUBRICANT & GLIDANT EXCIPIENT DEMAND BY TYPE

      12. 5.12 Preservatives

        $82.00

        1. Table | PRESERVATIVE EXCIPIENT DEMAND BY TYPE

      13. 5.13 Other Applications

        $82.00

        1. Table | OTHER APPLICATIONS FOR EXCIPIENTS BY TYPE

    6. 6 INDUSTRY STRUCTURE

      $5,132.00

      1. 6.1 General

        $92.00

        1. Table | US EXCIPIENT SALES BY COMPANY, 2013

      2. 6.2 Market Share

        $132.00

        1. CHART V-1 US EXCIPIENT MARKET SHARE, 2013

      3. 6.3 Competitive Strategies

        $491.00

        1. 6.3.1 Industry Restructuring

          $83.00

          1. Table | SELECTED ACQUISITIONS & DIVESTITURES

        2. 6.3.2 Cooperative Agreements

          $156.00

          1. Table | SELECTED COOPERATIVE AGREEMENTS

        3. 6.3.3 Marketing & Distribution

          $82.00

        4. 6.3.4 Research & Development

          $82.00

        5. 6.3.5 Manufacturing

          $82.00

      4. 6.4 Company Profiles

        $4,692.00

        1. 6.4.1 Akzo Nobel NV

          $82.00

        2. 6.4.2 Archer-Daniels-Midland Company

          $87.00

        3. 6.4.3 Ashland Incorporated

          $198.00

        4. 6.4.4 Associated British Foods plc

          $172.00

        5. 6.4.5 Avantor Performance Materials Incorporated

          $94.00

        6. 6.4.6 BASF SE

          $235.00

        7. 6.4.7 Berkshire Hathaway Incorporated

          $91.00

        8. 6.4.8 Berwind Corporation

          $146.00

        9. 6.4.9 Cabot Corporation

          $82.00

        10. 6.4.10 Cargill Incorporated

          $186.00

        11. 6.4.11 Celanese Corporation

          $82.00

        12. 6.4.12 Croda International plc

          $112.00

        13. 6.4.13 Dow Chemical Company

          $318.00

        14. 6.4.14 DuPont (EI) de Nemours

          $121.00

        15. 6.4.15 Eastman Chemical Company

          $111.00

        16. 6.4.16 Evonik Industries AG

          $154.00

        17. 6.4.17 Ferro Corporation

          $82.00

        18. 6.4.18 FibroGen Incorporated

          $82.00

        19. 6.4.19 FLAVORx Incorporated

          $82.00

        20. 6.4.20 FMC Corporation

          $153.00

        21. 6.4.21 GELITA AG

          $82.00

        22. 6.4.22 Generichem Corporation

          $82.00

        23. 6.4.23 Huber (JM) Corporation

          $167.00

        24. 6.4.24 Huntsman Corporation

          $82.00

        25. 6.4.25 Ingredion Incorporated

          $82.00

        26. 6.4.26 Innophos Holdings Incorporated

          $82.00

        27. 6.4.27 Kraft Foods Group Incorporated

          $82.00

        28. 6.4.28 Kuraray Company Limited

          $82.00

        29. 6.4.29 Ligand Pharmaceuticals Incorporated

          $90.00

        30. 6.4.30 LyondellBasell Industries NV

          $82.00

        31. 6.4.31 Merck KGaA

          $82.00

        32. 6.4.32 Mutchler Incorporated

          $82.00

        33. 6.4.33 Nitta Gelatin Incorporated

          $82.00

        34. 6.4.34 NutraSweet Company

          $82.00

        35. 6.4.35 Pfanstiehl Incorporated

          $82.00

        36. 6.4.36 Procter & Gamble Company

          $82.00

        37. 6.4.37 Rettenmaier (J.) &Söhne GmbH & Company KG

          $128.00

        38. 6.4.38 Roquette Frères SA

          $195.00

        39. 6.4.39 Royal Dutch Shell plc

          $82.00

        40. 6.4.40 Sasol Limited

          $104.00

        41. 6.4.41 Shin-Etsu Chemical Company Limited

          $114.00

        42. 6.4.42 Solvay SA

          $82.00

        43. 6.4.43 Stepan Company

          $82.00

        44. 6.4.44 Tate & Lyle plc

          $127.00

        45. 6.4.45 Tessenderlo Group NV

          $82.00

        46. 6.4.46 USG Corporation

          $82.00

        47. 6.4.47 Wacker Chemie AG

          $127.00

      5. 6.5 Other Companies Mentioned in Study

        $85.00

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