Pharmaceutical Chemicals

Gains will accelerate from the average pace of the 2009-2014 period, led by the introduction of new therapies for Alzheimer’s disease, cancer, diabetes, heart failure, and healthcare-associated infections.

US demand to rise 6.5% annually through 2019

US demand for pharmaceutical chemicals is expected to increase 6.5 percent annually to $46.9 billion in 2019. Gains will accelerate from the average pace of the 2009-2014 period, led by the introduction of new therapies for Alzheimer’s disease, cancer, diabetes, heart failure, and healthcare-associated infections. The value of pharmaceutical chemicals demand will remain fairly evenly divided between the merchant market and the captive and contract production segment. The merchant segment will see favorable growth based on drug patent expirations and the increasing availability of many first-time generic medicines. The value of captive and contract production output will benefit from new product introductions, especially breakthrough therapies for Alzheimer’s disease, cancer, and other presently incurable conditions.

Central nervous system chemicals to remain largest segment

Active ingredients of central nervous system agents will remain the largest therapeutic group served by pharmaceutical chemicals based on value and will post above average revenue growth. Demand in this therapeutic group will benefit from the introduction of new high value-added compounds for Alzheimer’s disease, multiple sclerosis, and rheumatoid arthritis; the penetration into the marketplace of new generic drugs for arthritic pain, epilepsy, glaucoma, and schizophrenia; and the expanding use of over-the-counter pain relievers and ophthalmic solutions for self-treatment.

Hormones & related agents to be fastest growing types

Led by active ingredients of anticancer, antidiabetic, and hormone replacement formulations, hormones and related agents will post the fastest growth in value among all pharmaceutical chemicals. Based on the introduction of new antithrombolytic and heart failure therapies, cardiovascular compounds will reverse a recent downturn and expand moderately in demand value. The development of new antibiotics under the FDA’s Qualified Infectious Disease Product program, coupled with an increasing patient volume for new hepatitis C treatments, will keep revenues of anti-infective chemicals rising.

High value-added nutrients, herbal extracts, and marine derivatives for specialty adult and pediatric preparations will lead to moderate growth in nutritional chemicals demand. Advances in vaccines, especially types for viral disorders, will boost growth in value of biological chemicals. Respiratory chemicals demand will advance slowly, but will improve on a recent downturn based on new asthma and chronic obstructive pulmonary disease (COPD) therapies.

Study coverage

This Freedonia industry study analyzes the $34.2 billion US pharmaceutical chemical industry. It presents historical demand data (2004, 2009 and 2014) and forecasts (2019 and 2024) by chemical type (e.g., central nervous system, hormones and related, cardiovascular, anti-infective, nutritional, biological, respiratory, gastrointestinal, dermatological). The study also considers market environment factors, details industry structure, evaluates company market share, and profiles 31 industry participants, including Teva Pharmaceutical Industries, Royal DSM, and Aurobindo Pharma.

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Purchase Pharmaceutical Chemicals by the Section

  1. Pharmaceutical Chemicals

    $5,200.00

    1. 1 INTRODUCTION

      $82.00

    2. 2 EXECUTIVE SUMMARY

      $89.00

      1. Table | PHARMACEUTICAL CHEMICALS DEMAND

    3. 3 MARKET ENVIRONMENT

      $1,234.00

      1. 3.1 General

        $82.00

      2. 3.2 Macroeconomic Factors

        $156.00

        1. Table | MACROECONOMIC INDICATORS

      3. 3.3 Demographic Patterns

        $99.00

        1. Table | RESIDENT POPULATION BY AGE GROUP

      4. 3.4 Healthcare Trends

        $633.00

        1. 3.4.1 Health Insurance Reforms

          $90.00

          1. Table | HEALTH INSURANCE COVERAGE OF THE US POPULATION, 2004-2014

        2. 3.4.2 Medical Conditions

          $128.00

          1. Table | ACUTE CONDITIONS BY TYPE

          2. Table | CHRONIC CONDITIONS BY TYPE

        3. 3.4.3 National Health Expenditures

          $206.00

          1. Table | NATIONAL HEALTH EXPENDITURES BY SPENDING CATEGORY

          2. Table | NATIONAL HEALTH EXPENDITURES BY FUNDING SOURCE

        4. 3.4.4 Medical Providers

          $108.00

          1. Table | MEDICAL PROVIDERS

        5. 3.4.5 Patient Activity

          $85.00

          1. Table | PATIENT ACTIVITY

      5. 3.5 Pharmaceutical Industry Overview

        $333.00

        1. 3.5.1 Regulation

          $82.00

        2. 3.5.2 Research & Development

          $82.00

        3. 3.5.3 Product Shipments

          $192.00

          1. Table | PHARMACEUTICAL SHIPMENTS BY THERAPEUTIC GROUP

          2. CHART II-1 PHARMACEUTICAL SHIPMENTS BY THERAPEUTIC GROUP, 2019

          3. Table | PHARMACEUTICAL SHIPMENTS BY DISTRIBUTION STATUS

          4. Table | PHARMACEUTICAL SHIPMENTS BY COMMERCIAL STATUS

    4. 4 PHARMACEUTICAL CHEMICALS OVERVIEW

      $348.00

      1. 4.1 General

        $82.00

      2. 4.2 Historical Demand Patterns

        $82.00

        1. Table | PHARMACEUTICAL CHEMICALS DEMAND, 2004-2014

      3. 4.3 US Trade

        $82.00

        1. Table | US TRADE IN PHARMACEUTICAL CHEMICALS

      4. 4.4 International Markets

        $82.00

        1. Table | WORLD PHARMACEUTICAL CHEMICALS MERCHANT DEMAND

      5. 4.5 Therapeutic Groups

        $82.00

        1. Table | PHARMACEUTICAL CHEMICALS DEMAND BY THERAPEUTIC GROUP

        2. CHART III-1 PHARMACEUTICAL CHEMICALS DEMAND BY THERAPEUTIC GROUP, 2019

      6. 4.6 Merchant Market Demand

        $82.00

        1. Table | PHARMACEUTICAL CHEMICALS: MERCHANT MARKET DEMAND BY THERAPEUTIC GROUP

      7. 4.7 Captive & Contract Production

        $82.00

        1. Table | PHARMACEUTICAL CHEMICALS: CAPTIVE & CONTRACT PRODUCTION OUTPUT

      8. 4.8 Ethical Pharmaceutical Chemicals

        $82.00

        1. Table | PHARMACEUTICAL CHEMICALS: ETHICAL PHARMACEUTICALS DEMAND

      9. 4.9 Over-the-Counter Pharmaceutical Chemicals

        $82.00

        1. Table | PHARMACEUTICAL CHEMICALS: OVER-THE-COUNTER PHARMACEUTICALS DEMAND

    5. 5 CENTRAL NERVOUS SYSTEM CHEMICALS

      $2,417.00

      1. 5.1 General

        $82.00

        1. Table | CENTRAL NERVOUS SYSTEM (CNS) CHEMICALS DEMAND

        2. CHART IV-1 CENTRAL NERVOUS SYSTEM CHEMICALS DEMAND BY TYPE, 2019

      2. 5.2 Psychotherapeutic Agents

        $254.00

        1. Table | PSYCHOTHERAPEUTIC CHEMICALS DEMAND

        2. 5.2.1 Antipsychotic Agents

          $82.00

        3. 5.2.2 Antidepressants

          $82.00

        4. 5.2.3 Anti-Anxiety Agents

          $82.00

        5. 5.2.4 OTC Sedatives

          $82.00

      3. 5.3 Neurological Agents

        $475.00

        1. Table | NEUROLOGICAL CHEMICALS DEMAND

        2. 5.3.1 Anticonvulsants

          $82.00

        3. 5.3.2 Multiple Sclerosis Treatments

          $82.00

        4. 5.3.3 Alzheimer's Disease Treatments

          $146.00

        5. 5.3.4 Parkinson's Disease Treatments

          $150.00

        6. 5.3.5 Other Neurological Agents

          $82.00

      4. 5.4 Pain Control Agents

        $774.00

        1. Table | PAIN CONTROL CHEMICALS DEMAND

        2. 5.4.1 Narcotic Analgesics

          $190.00

        3. 5.4.2 Over-the-Counter Analgesics

          $82.00

        4. 5.4.3 Ethical Nonsteroidal Anti-Inflammatory Agents

          $128.00

        5. 5.4.4 Antimigraine Agents

          $122.00

        6. 5.4.5 Anesthetics

          $174.00

        7. 5.4.6 Hyaluronic Acid

          $82.00

      5. 5.5 Rheumatoid Arthritis Treatment Chemicals

        $185.00

        1. Table | RHEUMATOID ARTHRITIS TREATMENT CHEMICALS DEMAND BY SOURCE OF SUPPLY

        2. 5.5.1 Monoclonal Antibodies

          $93.00

        3. 5.5.2 Other Arthritis Treatments

          $82.00

      6. 5.6 Ophthalmic Agents

        $320.00

        1. Table | OPHTHALMIC CHEMICALS DEMAND

        2. 5.6.1 Anti-Angiogenic Agents

          $83.00

        3. 5.6.2 Glaucoma Treatments

          $82.00

        4. 5.6.3 Other Ophthalmic Agents

          $123.00

      7. 5.7 Other Central Nervous System Chemicals

        $338.00

        1. Table | OTHER CENTRAL NERVOUS SYSTEM CHEMICALS DEMAND

        2. 5.7.1 CNS Stimulants

          $82.00

        3. 5.7.2 Muscle Relaxants

          $84.00

        4. 5.7.3 Smoking Cessation Compounds

          $82.00

        5. 5.7.4 Anti-Obesity Agents

          $82.00

    6. 6 HORMONES & RELATED CHEMICALS

      $1,743.00

      1. 6.1 General

        $82.00

        1. Table | HORMONES & RELATED CHEMICALS DEMAND

        2. CHART V-1 HORMONES & RELATED CHEMICALS DEMAND BY TYPE, 2019

      2. 6.2 Anticancer Agents

        $781.00

        1. Table | ANTICANCER CHEMICALS DEMAND

        2. 6.2.1 Monoclonal Antibodies

          $164.00

        3. 6.2.2 Enzyme Inhibitors

          $195.00

        4. 6.2.3 Growth Factors

          $82.00

        5. 6.2.4 Immunomodulating Agents

          $82.00

        6. 6.2.5 Other Anticancer Agents

          $160.00

        7. 6.2.6 Selected Anticancer Agents in Development

          $112.00

      3. 6.3 Antidiabetic Agents

        $355.00

        1. Table | ANTIDIABETIC CHEMICALS DEMAND

        2. 6.3.1 Insulins

          $87.00

        3. 6.3.2 DPP-4 Inhibitors

          $82.00

        4. 6.3.3 Biguanides

          $82.00

        5. 6.3.4 Thiazolidinediones

          $82.00

        6. 6.3.5 GLP-1 Agonists

          $82.00

        7. 6.3.6 Sulfonylureas

          $82.00

        8. 6.3.7 Other Antidiabetic Agents

          $82.00

      4. 6.4 Hormone Replacement Therapies

        $328.00

        1. Table | HORMONE REPLACEMENT CHEMICALS DEMAND

        2. 6.4.1 Thyroid Agents

          $82.00

        3. 6.4.2 Erythropoietins

          $82.00

        4. 6.4.3 Estrogens

          $82.00

        5. 6.4.4 Growth Hormones

          $82.00

        6. 6.4.5 Other Hormone & Related Replacement Therapies

          $94.00

      5. 6.5 Bisphosphonates & Related Agents

        $82.00

        1. Table | BISPHOSPHONATES & RELATED CHEMICALS DEMAND BY SOURCE OF SUPPLY

      6. 6.6 Hormonal Contraceptives

        $86.00

        1. Table | HORMONAL CONTRACEPTIVE CHEMICALS DEMAND BY SOURCE OF SUPPLY

        2. 6.6.1 Combination Oral Contraceptives

          $82.00

        3. 6.6.2 Progestin-Only Pills

          $82.00

        4. 6.6.3 Other Hormonal Contraceptives

          $82.00

      7. 6.7 Other Hormones & Related Agents

        $82.00

        1. Table | OTHER HORMONES & RELATED CHEMICALS DEMAND BY SOURCE OF SUPPLY

    7. 7 CARDIOVASCULAR CHEMICALS

      $588.00

      1. 7.1 General

        $82.00

        1. Table | CARDIOVASCULAR CHEMICALS DEMAND

        2. CHART VI-1 CARDIOVASCULAR CHEMICALS DEMAND BY TYPE, 2019

      2. 7.2 Cholesterol Reducers

        $82.00

        1. Table | CHOLESTEROL-REDUCING CHEMICALS DEMAND BY SOURCE OF SUPPLY

      3. 7.3 Antithrombolytic Agents

        $124.00

        1. Table | ANTITHROMBOLYTIC CHEMICALS DEMAND BY SOURCE OF SUPPLY

        2. 7.3.1 Patent Expirations

          $82.00

        3. 7.3.2 Marketed Products

          $87.00

      4. 7.4 Beta Blockers

        $82.00

        1. Table | BETA BLOCKER CHEMICALS DEMAND BY SOURCE OF SUPPLY

      5. 7.5 Calcium Channel Blockers

        $82.00

        1. Table | CALCIUM CHANNEL BLOCKER CHEMICALS DEMAND BY SOURCE OF SUPPLY

      6. 7.6 Angiotensin II Receptor Antagonists

        $82.00

        1. Table | ANGIOTENSIN II ANTAGONIST CHEMICALS DEMAND BY SOURCE OF SUPPLY

      7. 7.7 ACE Inhibitors

        $82.00

        1. Table | ACE INHIBITOR CHEMICALS DEMAND BY SOURCE OF SUPPLY

      8. 7.8 Diuretics

        $82.00

        1. Table | DIURETIC CHEMICALS DEMAND BY SOURCE OF SUPPLY

      9. 7.9 Other Cardiovascular Drugs

        $155.00

        1. Table | OTHER CARDIOVASCULAR CHEMICALS DEMAND BY SOURCE OF SUPPLY

        2. 7.9.1 Alpha Adrenergic Agonists

          $82.00

        3. 7.9.2 Anti-Arrhythmics

          $82.00

        4. 7.9.3 Bradykinin B2 Receptor Antagonists

          $82.00

        5. 7.9.4 Cardiac Glycosides

          $82.00

        6. 7.9.5 Endothelin Receptor Antagonists

          $82.00

        7. 7.9.6 Vasodilators

          $82.00

        8. 7.9.7 All Other Cardiovascular Drugs

          $82.00

    8. 8 ANTI-INFECTIVE CHEMICALS

      $1,262.00

      1. 8.1 General

        $82.00

        1. Table | ANTI-INFECTIVE CHEMICALS DEMAND

        2. CHART VII-1 ANTI-INFECTIVE CHEMICALS DEMAND BY TYPE, 2019

      2. 8.2 Antiviral Agents

        $513.00

        1. Table | ANTIVIRAL CHEMICALS DEMAND

        2. 8.2.1 Hepatitis Antiviral Agents

          $159.00

        3. 8.2.2 HIV Antiviral Agents

          $177.00

        4. 8.2.3 Other Antiviral Agents

          $153.00

      3. 8.3 Antibiotics

        $516.00

        1. Table | ANTIBIOTIC CHEMICALS DEMAND

        2. 8.3.1 Penicillins

          $82.00

        3. 8.3.2 Macrolides

          $82.00

        4. 8.3.3 Cephalosporins

          $82.00

        5. 8.3.4 Quinolones

          $82.00

        6. 8.3.5 Other Antibiotics

          $245.00

      4. 8.4 Oral Antiseptics

        $82.00

        1. Table | ORAL ANTISEPTICS CHEMICALS DEMAND BY SOURCE OF SUPPLY

      5. 8.5 Other Anti-Infective Agents

        $143.00

        1. Table | OTHER ANTI-INFECTIVE CHEMICALS DEMAND

        2. 8.5.1 Antifungal Agents

          $82.00

        3. 8.5.2 Antimalarial Agents

          $82.00

    9. 9 NUTRITIONAL CHEMICALS

      $2,115.00

      1. 9.1 General

        $82.00

        1. Table | NUTRITIONAL CHEMICALS DEMAND

        2. CHART VIII-1 NUTRITIONAL CHEMICALS DEMAND BY TYPE, 2019

      2. 9.2 Herbal & Related Ingredients

        $688.00

        1. Table | HERBAL & RELATED CHEMICALS DEMAND

        2. 9.2.1 Herbal & Botanical Extracts

          $461.00

        3. 9.2.2 Fish Oils

          $90.00

        4. 9.2.3 Marine & Related Extracts

          $116.00

      3. 9.3 Nutrients

        $669.00

        1. Table | NUTRIENT CHEMICALS DEMAND

        2. 9.3.1 Proteins

          $133.00

        3. 9.3.2 Fibers

          $193.00

        4. 9.3.3 Probiotics

          $82.00

        5. 9.3.4 Other Nutrients

          $301.00

      4. 9.4 Bulk Minerals

        $216.00

        1. Table | BULK MINERALS DEMAND

        2. 9.4.1 Electrolytes

          $82.00

        3. 9.4.2 Essential Minerals

          $121.00

        4. 9.4.3 Trace Minerals

          $82.00

      5. 9.5 Bulk Vitamins

        $495.00

        1. Table | BULK VITAMINS DEMAND

        2. 9.5.1 Vitamin C

          $82.00

        3. 9.5.2 Vitamin A

          $82.00

        4. 9.5.3 B-Group Vitamins

          $200.00

        5. 9.5.4 Vitamin E

          $82.00

        6. 9.5.5 Other Vitamins

          $82.00

    10. 10 BIOLOGICAL CHEMICALS

      $596.00

      1. 10.1 General

        $82.00

        1. Table | BIOLOGICAL CHEMICALS DEMAND

      2. 10.2 Vaccines

        $227.00

        1. Table | VACCINE CHEMICALS DEMAND BY SOURCE OF SUPPLY

        2. 10.2.1 Attenuated Vaccines

          $82.00

        3. 10.2.2 Conjugate Vaccines

          $82.00

        4. 10.2.3 Inactivated Vaccines

          $82.00

        5. 10.2.4 Recombinant Vaccines

          $82.00

        6. 10.2.5 Toxoid Vaccines

          $82.00

        7. 10.2.6 Vaccines in Development

          $82.00

      3. 10.3 Blood Derivatives

        $331.00

        1. Table | BLOOD DERIVATIVE CHEMICALS DEMAND BY SOURCE OF SUPPLY

        2. 10.3.1 Plasma Protein Therapies

          $174.00

        3. 10.3.2 Cellular Components

          $82.00

        4. 10.3.3 Other Blood-Related Chemicals

          $82.00

    11. 11 RESPIRATORY CHEMICALS

      $479.00

      1. 11.1 General

        $82.00

        1. Table | RESPIRATORY CHEMICALS DEMAND

        2. CHART X-1 RESPIRATORY CHEMICALS DEMAND BY TYPE, 2019

      2. 11.2 Bronchodilators

        $107.00

        1. Table | BRONCHODILATOR CHEMICALS DEMAND BY SOURCE OF SUPPLY

      3. 11.3 Antihistamines

        $82.00

        1. Table | ANTIHISTAMINE CHEMICALS DEMAND

      4. 11.4 Inhaled Corticosteroids

        $82.00

        1. Table | CORTICOSTEROID CHEMICALS DEMAND

      5. 11.5 Antitussives

        $82.00

        1. Table | ANTITUSSIVE CHEMICALS DEMAND

      6. 11.6 Other Respiratory Chemicals

        $173.00

        1. Table | OTHER RESPIRATORY CHEMICALS DEMAND

        2. 11.6.1 Decongestants

          $82.00

        3. 11.6.2 Expectorants & Mucolytics

          $82.00

        4. 11.6.3 Omalizumab

          $82.00

        5. 11.6.4 Leukotriene Receptor Antagonists (LRAs)

          $82.00

        6. 11.6.5 Selective Phosphodiesterase-4 Inhibitors

          $82.00

        7. 11.6.6 Ivacaftor

          $82.00

        8. 11.6.7 Nintedanib

          $82.00

        9. 11.6.8 Pirfenidone

          $82.00

        10. 11.6.9 Surfactants

          $82.00

    12. 12 GASTROINTESTINAL CHEMICALS

      $437.00

      1. 12.1 General

        $82.00

        1. Table | GASTROINTESTINAL CHEMICALS DEMAND

        2. CHART XI-1 GASTROINTESTINAL CHEMICALS DEMAND BY TYPE, 2019

      2. 12.2 Proton Pump Inhibitors

        $82.00

        1. Table | PROTON PUMP INHIBITORS CHEMICALS DEMAND

      3. 12.3 Anti-Emetic Agents

        $82.00

        1. Table | ANTI-EMETIC CHEMICALS DEMAND BY SOURCE OF SUPPLY

      4. 12.4 Laxatives

        $82.00

        1. Table | OTC LAXATIVE CHEMICALS DEMAND

      5. 12.5 Gastrointestinal Anti-Inflammatory Agents

        $82.00

        1. Table | GASTROINTESTINAL ANTI-INFLAMMATORY CHEMICALS DEMAND BY SOURCE OF SUPPLY

      6. 12.6 OTC Antacids

        $82.00

        1. Table | OTC ANTACID CHEMICALS DEMAND

      7. 12.7 Antidiarrheals

        $82.00

        1. Table | ANTIDIARRHEAL CHEMICALS DEMAND

      8. 12.8 Other Gastrointestinal Agents

        $82.00

        1. Table | OTHER GASTROINTESTINAL CHEMICALS DEMAND BY SOURCE OF SUPPLY

    13. 13 DERMATOLOGICAL CHEMICALS

      $420.00

      1. 13.1 General

        $82.00

        1. Table | DERMATOLOGICAL CHEMICALS DEMAND

        2. CHART XII-1 DERMATOLOGICAL CHEMICALS DEMAND BY TYPE, 2019

      2. 13.2 Antipsoriatic Agents

        $106.00

        1. Table | ANTIPSORIATIC CHEMICALS DEMAND

      3. 13.3 Dermatological Anti-Infective Agents

        $121.00

        1. Table | DERMATOLOGICAL ANTI-INFECTIVE CHEMICALS DEMAND

        2. 13.3.1 Antibacterial Compounds

          $82.00

        3. 13.3.2 Antifungal Compounds

          $82.00

        4. 13.3.3 Other Dermatological Anti-Infective Compounds

          $82.00

      4. 13.4 External Analgesics

        $82.00

        1. Table | EXTERNAL ANALGESIC CHEMICALS DEMAND

      5. 13.5 Anti-Acne Agents

        $82.00

        1. Table | ANTI-ACNE CHEMICALS DEMAND

      6. 13.6 Other Dermatological Chemicals

        $82.00

        1. Table | OTHER DERMATOLOGICAL CHEMICALS DEMAND

    14. 14 OTHER PHARMACEUTICAL CHEMICALS

      $258.00

      1. 14.1 General

        $82.00

        1. Table | OTHER PHARMACEUTICAL CHEMICALS DEMAND

      2. 14.2 Genito-Urinary Chemicals

        $118.00

        1. Table | GENITO-URINARY CHEMICALS DEMAND

        2. 14.2.1 Erectile Dysfunction (ED) Treatments

          $82.00

        3. 14.2.2 Benign Prostate Hyperplasia (BPH) Treatments

          $82.00

        4. 14.2.3 Overactive Bladder Treatments

          $82.00

      3. 14.3 All Other Pharmaceutical Chemicals

        $97.00

        1. Table | ALL OTHER PHARMACEUTICAL CHEMICALS DEMAND

        2. 14.3.1 Antitransplant Rejection Agents

          $82.00

        3. 14.3.2 Chelating Agents

          $82.00

    15. 15 INDUSTRY STRUCTURE

      $2,518.00

      1. 15.1 General

        $82.00

        1. Table | PHARMACEUTICAL CHEMICALS: US MERCHANT SALES BY COMPANY, 2014

      2. 15.2 Market Share

        $155.00

        1. CHART XIV-1 PHARMACEUTICAL CHEMICALS: US MERCHANT MARKET SHARE, 2014

      3. 15.3 Competitive Strategies

        $82.00

      4. 15.4 Mergers & Acquisitions

        $89.00

        1. Table | SELECTED ACQUISITIONS & DIVESTITURES

      5. 15.5 Licensing & Related Agreements

        $82.00

        1. Table | SELECTED COOPERATIVE AGREEMENTS

      6. 15.6 Marketing & Distribution

        $82.00

      7. 15.7 Manufacturing

        $82.00

      8. 15.8 Company Profiles

        $1,728.00

        1. 15.8.1 Aceto Corporation

          $82.00

        2. 15.8.2 Ajinomoto Company Incorporated

          $82.00

        3. 15.8.3 Albemarle Corporation

          $82.00

        4. 15.8.4 American Pacific Corporation

          $82.00

        5. 15.8.5 Aptuit LLC

          $82.00

        6. 15.8.6 Aurobindo Pharma Limited

          $82.00

        7. 15.8.7 BASF SE

          $82.00

        8. 15.8.8 Biocon Limited

          $99.00

        9. 15.8.9 Cambrex Corporation

          $82.00

        10. 15.8.10 Cipla Limited

          $82.00

        11. 15.8.11 Daiichi Sankyo Company Limited

          $82.00

        12. 15.8.12 Dishman Pharmaceuticals and Chemicals Limited

          $82.00

        13. 15.8.13 Dr. Reddy's Laboratories Limited

          $82.00

        14. 15.8.14 Fabbrica Italiana Sintetici SpA

          $82.00

        15. 15.8.15 FMC Corporation

          $82.00

        16. 15.8.16 FUJIFILM Holdings Corporation

          $82.00

        17. 15.8.17 Johnson & Johnson

          $82.00

        18. 15.8.18 Johnson Matthey plc

          $82.00

        19. 15.8.19 Kyowa Hakko Kirin Company Limited

          $82.00

        20. 15.8.20 Lonza Group Limited

          $82.00

        21. 15.8.21 Lupin Limited

          $82.00

        22. 15.8.22 Mallinckrodt plc

          $82.00

        23. 15.8.23 Novartis AG

          $82.00

        24. 15.8.24 Novasep Holding SAS

          $82.00

        25. 15.8.25 Pfanstiehl Incorporated

          $82.00

        26. 15.8.26 Royal DSM NV

          $117.00

        27. 15.8.27 SI Group Incorporated

          $82.00

        28. 15.8.28 Sigma-Aldrich Corporation

          $82.00

        29. 15.8.29 Sun Pharmaceutical Industries Limited

          $99.00

        30. 15.8.30 Teva Pharmaceutical Industries Limited

          $82.00

        31. 15.8.31 WuXi PharmaTech Cayman Incorporated

          $82.00

      9. 15.9 Additional Companies in the Pharmaceutical Chemicals Industry

        $268.00

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